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Generic Celebrex (Celecoxib) is a nonsteroidal anti-inflammatory drug approved for the treatment of osteoarthritis and rheumatoid arthritis, pain, menstrual cramps, and colonic polyps.

Generic Celebrex (Celecoxib) is approved to treat the joint pain, stiffness, and swelling of osteoarthritis and adult rheumatoid arthritis. And CELEBREX was designed to target the source of joint pain. CELEBREX is one of the most studied arthritis medicines on the market.

Generic Celebrex (Celecoxib) reduces the number of colorectal polyps in patients with Familial Adenomatous Polyposis (FAP). FAP is an inherited disorder in which the rectum and colon are covered with many polyps. Generic Celebrex (Celecoxib) should be used along with the usual care for FAP patients such as surgery and monitoring of the lower gastrointestinal tract.

Generic Celebrex (Celecoxib) works to relieve arthritis pain by targeting a certain enzyme in the body. An enzyme is a protein that causes chemical changes in other substances in the body. The enzyme that Generic Celebrex (Celecoxib) targets is called COX-2. The COX-2 enzyme plays a key role in causing both pain and inflammation.

Active Ingredients: celecoxib
Other Ingredients: croscarmellose sodium, edible inks, gelatin, lactose monohydrate, magnesium stearate, povidone, sodium lauryl sulfate and titanium dioxide.
Mechanism of Action: Generic Celebrex (Celecoxib) is a nonsteroidal anti-inflammatory drug that exhibits anti-inflammatory, analgesic, and antipyretic activities in animal models. The mechanism of action of CELEBREX is believed to be due to inhibition of prostaglandin synthesis, primarily via inhibition of cyclooxygenase-2 (COX-2), and at therapeutic concentrations in humans, Generic Celebrex (Celecoxib) does not inhibit the cyclooxygenase-1 (COX-1) isoenzyme. In animal colon tumor models, celecoxib reduced the incidence and multiplicity of tumors.

Keep out of the reach of children in a container that small children cannot open.
Store at room temperature between 15—30 degrees C (59—86 degrees F). Protect from moisture. Keep container tightly closed. Throw away any unused medicine after the expiration date.

Your doctor will determine the dose you should take, depending on your condition and medical history. Avoid taking Generic Celebrex (Celecoxib) with antacids that contain calcium carbonate and magnesium/aluminum combination products, because they may reduce the amount of Generic Celebrex (Celecoxib) your body absorbs.

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
When OVERDOSE is suspected, seek medical attention immediately. Symptoms of overdose include nausea, vomiting, stomach upset, headache, buzzing in the ears, blurred visions, dizziness, unable to urinate, slow and shallow breathing and coma.

You should not take Celebrex if you:
• have had an allergic-type reaction to sulfa drugs
• have had asthma, hives or allergic-type reactions after taking aspirin
• Are in late pregnancy
• Are having or have recently had a certain kind of heart surgery called coronary artery bypass graft

All medicines have possible side effects. Although Generic Celebrex (Celecoxib) is usually well-tolerated, in clinical trials some common side effects were indigestion, diarrhea, and abdominal pain.

Other side effects may include: headache, upper respiratory tract infection, sinus inflammation, stomach pain, nausea.

Generic Celebrex (Celecoxib) may increase the chance of serious heart problems, such as heart attacks or strokes, which can lead to death. Serious skin reactions or stomach and intestine problems, such as bleeding and ulcers, can occur without warning and may cause death. As always, patients should discuss their individual health history with their doctors to understand these risks.

Prior to Generic Celebrex (Celecoxib) Treatment inform your doctor if you are taking or have taken any of the following medicines:
• Aspirin or salicylates
• Over the counter cold medications, allergy medicines, or analgesics such as ibuprofen, naproxen, or Ketoprofen
• Diuretics such as furosemide
• ACE inhibitors such as benazepril
• corticosteroids such as prednisone
• anticoagulants such as Warfarin
• lithium
• fluconazole

When under the influence of these medicines, you may require adjustments to Generic Celebrex (Celecoxib) dosage or you may be advised to entirely cease Generic Celebrex (Celecoxib) medication.

Let your prescriber or health care professional know if your pain continues; do not take with other pain-killers without advice. If you get flu-like symptoms (fever, chills, muscle aches and pains), call your prescriber or health care professional; do not treat yourself.