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Generic Altace is used in the treatment of high blood pressure. It is effective when used alone or in combination with other high blood pressure medications, especially thiazide-type water pills (diuretics). Altace works by preventing the conversion of a chemical in your blood called angiotensin I into a more potent substance that increases salt and water retention in your body. It also enhances blood flow in your circulatory system. It is a member of the group of drugs called ACE inhibitors.

Generic Altace is prescribed to reduce the chances of heart attack, stroke, and heart-related death in people 55 years or older who are in danger of such an event. Typical candidates include those who suffer from coronary artery disease, poor circulation, stroke, or diabetes and have at least one other risk factor, such as high blood pressure, high cholesterol levels, low HDL ("good") cholesterol, or cigarette smoking.
If you do suffer a heart attack and develop heart failure, Altace can be prescribed to prevent the condition from getting worse.

Active Ingredients: Ramipril
Other Ingredients: Pregelatinized starch NF, gelatin, and titanium dioxide.
Class and Mechanism: Altace belongs in a class of drugs called angiotensin converting enzyme (ACE) inhibitors which are used for treating high blood pressure and heart failure and for preventing kidney failure due to high blood pressure and diabetes. ACE is important because it produces the protein, angiotensin II. Angiotensin II contracts the muscles of most arteries in the body, including the heart, thereby narrowing the arteries and elevating the blood pressure. In the kidney, the narrowing caused by angiotensin II also increases blood pressure and decreases the flow of blood. ACE inhibitors such as Altace lower blood pressure by reducing the production of angiotensin II, thereby relaxing the arterial muscles and enlarging the arteries. The enlargement of the arteries throughout the body reduces the blood pressure against which the heart must pump blood, and it becomes easier for the heart to pump blood. The arteries supplying the heart with blood also enlarge. This increases the flow of blood and oxygen to the heart, and this improves further the ability of the heart to pump blood. The effects of ACE inhibitors are particularly beneficial to people with congestive heart failure. In the kidneys, the enlargement of the arteries also reduces blood pressure and increases blood flow. The FDA approved Altace in 1991.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of childrenin a container that small children cannot open.

Generic Altace comes as a capsule to take by mouth. It is usually taken once or twice a day with or without food. To help you remember to take Altace, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Altace exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the capsule whole, or open the capsule and sprinkle the contents on a small amount of applesauce (about 4 oz.) or in 4 oz. of water or apple juice. Eat or drink the entire mixture. This mixture can be prepared in advance and stored for 24 hours at room temperature or 48 hours in the refrigerator.
Your doctor will probably start you on a low dose of Altace and gradually increase your dose. Altace controls high blood pressure and heart failure but does not cure them. Continue to take Altace even if you feel well. Do not stop taking Altace without talking to your doctor.
Cautions If you develop swelling of the face around your lips, tongue, or throat or difficulty swallowing, difficulty breathing, swelling of arms and legs, or infection, sore throat, and fever, you should contact your doctor immediately. You may have a serious side effect of the drug and need emergency treatment.
You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how Altace affects you. To avoid dizzy or fainting spells, do not stand or sit up quickly, especially if you are an older person. Alcohol can make you more dizzy. Avoid alcoholic drinks.
If OVERDOSE is suspected seek emergency medical attention, Symptoms of a Altace overdose include extreme dizziness, weakness, fainting, and fatigue.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular regular dosing schedule. Do not take a double dose to make up for a missed one.

Do not use this medication if you are allergic to Altace or to any other ACE inhibitor, such as benazopril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), or trandolapril (Mavik).
Before using Altace, tell your doctor if you are allergic to any drugs, or if you have: kidney disease (or if you are on dialysis); liver disease; heart disease or congestive heart failure; diabetes; or a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.
If you have any of these conditions, you may not be able to use Altace, or you may need a dosage adjustment or special tests during treatment.
FOR WOMEN: do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Generic Altace could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Altace can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects: feeling light-headed, fainting; urinating more or less than usual, or not at all; fever, chills, body aches, flu symptoms; pale skin, easy bruising or bleeding; tired feeling, muscle weakness, and pounding or uneven heartbeats; chest pain; or swelling, rapid weight gain.
Less serious side effects may be more likely to occur, such as: cough; dizziness, drowsiness, headache; sleep problems (insomnia); decreased sex drive, impotence, or difficulty having an orgasm; nausea, vomiting; or mild skin itching or rash.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Before taking Generic Altace (Ramipril), tell your doctor if you are taking any of the following drugs: a potassium supplement such as K-Dur, Klor-Con, and others; salt substitutes that contain potassium; any of the diuretics (water pills) triamterene (Dyrenium, Maxzide, Dyazide), spironolactone (Aldactone), or amiloride (Midamor); any other diuretic (water pill) such as hydrochlorothiazide (HCTZ, HydroDiuril, others), furosemide (Lasix), bumetanide (Bumex), indapamide (Lozol), and others; or lithium (Lithobid, Eskalith, others).
You may not be able to take Altace, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above. Drugs other than those listed here may also interact with Altace or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

If you are going to have surgery, tell your prescriber or health care professional that you are using Altace.
Do not treat yourself for coughs, colds, or pain while you are using Altace without asking your prescriber or health care professional for advice.